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Michael R Hayden Selected Research

Pancreatitis

2/2009Acute hypertriglyceridemic pancreatitis during pregnancy due to homozygous lipoprotein lipase gene mutation.
5/2006Correction of feline lipoprotein lipase deficiency with adeno-associated virus serotype 1-mediated gene transfer of the lipoprotein lipase S447X beneficial mutation.
11/2005Gene therapy for lipoprotein lipase deficiency: working toward clinical application.
9/2004Long-term correction of murine lipoprotein lipase deficiency with AAV1-mediated gene transfer of the naturally occurring LPL(S447X) beneficial mutation.

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Michael R Hayden Research Topics

Disease

137Huntington Disease (Huntington's Disease)
02/2024 - 02/2002
47Neurodegenerative Diseases (Neurodegenerative Disease)
01/2024 - 05/2004
15Atherosclerosis
11/2017 - 01/2002
11Disease Progression
02/2024 - 11/2002
11Neoplasms (Cancer)
01/2022 - 01/2011
11Alzheimer Disease (Alzheimer's Disease)
01/2017 - 05/2004
10Inflammation (Inflammations)
01/2023 - 03/2009
9Tangier Disease
01/2015 - 10/2002
9Hypertriglyceridemia
01/2011 - 11/2002
8Mitochondrial Diseases (Mitochondrial Disease)
01/2023 - 02/2006
8Atrophy
06/2019 - 04/2002
8Drug-Related Side Effects and Adverse Reactions
01/2018 - 09/2007
8Type 2 Diabetes Mellitus (MODY)
01/2016 - 03/2007
7Insulin Resistance
11/2022 - 01/2008
7Multiple Sclerosis
11/2017 - 05/2015
7Cardiotoxicity
01/2017 - 09/2011
5Cognitive Dysfunction
10/2018 - 04/2005
5Hypoalphalipoproteinemias (Hypoalphalipoproteinemia)
08/2006 - 10/2002
4Gliosis
05/2023 - 06/2013
4Glucose Intolerance
01/2016 - 01/2010
4Cardiovascular Diseases (Cardiovascular Disease)
04/2015 - 01/2002
4Coronary Artery Disease (Coronary Atherosclerosis)
03/2012 - 10/2004
4Pancreatitis
02/2009 - 09/2004
3Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
04/2023 - 12/2016
3Neuroinflammatory Diseases
01/2023 - 06/2013
3Parkinson Disease (Parkinson's Disease)
01/2019 - 01/2016
3Ototoxicity
01/2018 - 12/2009
3Body Weight (Weight, Body)
04/2015 - 04/2010
3Obesity
03/2014 - 03/2009
3Hyperlipidemias (Hyperlipidemia)
08/2009 - 11/2002
3Juvenile Amyotrophic Lateral Sclerosis 2
01/2007 - 12/2003
2Seizures (Absence Seizure)
05/2023 - 10/2010
2Inborn Genetic Diseases (Disease, Hereditary)
01/2023 - 02/2010
2Hyperlipoproteinemia Type I (Lipoprotein Lipase Deficiency, Familial)
01/2023 - 05/2006
2Parkinsonian Disorders (Parkinsonism)
01/2019 - 01/2019
2Peripheral Nervous System Diseases (PNS Diseases)
01/2019 - 01/2015
2Genetic Predisposition to Disease (Genetic Predisposition)
01/2018 - 12/2009
2Hearing Loss (Hearing Impairment)
01/2018 - 12/2009
2Testicular Neoplasms (Testicular Cancer)
01/2018 - 11/2017

Drug/Important Bio-Agent (IBA)

46polyglutamineIBA
01/2023 - 02/2002
39Proteins (Proteins, Gene)FDA Link
01/2024 - 02/2002
21CholesterolIBA
04/2021 - 01/2002
18Huntingtin ProteinIBA
01/2023 - 08/2002
14Caspase 6IBA
10/2020 - 01/2011
13HDL CholesterolIBA
04/2015 - 11/2004
11N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
01/2019 - 03/2002
9pridopidineIBA
04/2023 - 01/2016
9Lipoprotein Lipase (Diacylglycerol Lipase)IBA
01/2023 - 09/2004
9LipidsIBA
01/2018 - 08/2003
9Triglycerides (Triacylglycerol)IBA
03/2014 - 11/2002
7DNA (Deoxyribonucleic Acid)IBA
11/2020 - 07/2002
7CaspasesIBA
01/2018 - 09/2002
7AnthracyclinesIBA
01/2017 - 09/2011
6Antisense OligonucleotidesIBA
01/2024 - 12/2011
6Sigma-1 ReceptorIBA
04/2023 - 01/2019
6laquinimodIBA
01/2023 - 01/2016
6Glucose (Dextrose)FDA LinkGeneric
11/2022 - 01/2008
6Insulin (Novolin)FDA Link
11/2022 - 01/2008
6ATP-Binding Cassette Transporters (ABC Transporters)IBA
03/2012 - 06/2003
5Brain-Derived Neurotrophic Factor (BDNF)IBA
05/2023 - 11/2010
5Apolipoproteins E (ApoE)IBA
01/2022 - 12/2005
5Cisplatin (Platino)FDA LinkGeneric
01/2018 - 12/2009
5Amyloid (Amyloid Fibrils)IBA
01/2017 - 12/2005
5Mutant Proteins (Protein, Mutant)IBA
01/2014 - 08/2002
5Opioid Analgesics (Opioids)IBA
05/2013 - 10/2010
4Apolipoprotein A-I (Apolipoprotein A1)IBA
01/2024 - 10/2004
4Steroid 12-alpha-Hydroxylase (CYP8B1)IBA
11/2022 - 04/2015
4Biomarkers (Surrogate Marker)IBA
01/2022 - 10/2005
4LDL Receptors (LDL Receptor)IBA
10/2019 - 04/2006
4HDL LipoproteinsIBA
11/2017 - 10/2005
4Glatiramer Acetate (Copaxone)FDA Link
11/2017 - 05/2015
4CalciumIBA
01/2016 - 08/2002
4Codeine (Codeine Phosphate)FDA LinkGeneric
01/2013 - 08/2011
4Lipoproteins (Lipoprotein)IBA
01/2011 - 02/2008
4Adenosine Triphosphate (ATP)IBA
02/2010 - 10/2002
3Bile Acids and Salts (Bile Acids)IBA
11/2022 - 01/2018
3Neuroprotective AgentsIBA
11/2021 - 12/2012
3Dopamine (Intropin)FDA LinkGeneric
01/2021 - 10/2005
3Peptides (Polypeptides)IBA
11/2017 - 01/2012
3Insulin-Like Growth Factor I (IGF-1)IBA
08/2016 - 04/2010
3Monoamine Oxidase (MAO)IBA
04/2016 - 12/2015
3Warfarin (Coumadin)FDA LinkGeneric
06/2014 - 09/2011
3TransferasesIBA
11/2013 - 12/2009
3Cytochrome P-450 CYP2D6 (CYP2D6)IBA
12/2012 - 08/2011
3stearoyl-coenzyme A (stearoyl-CoA)IBA
12/2009 - 01/2008
3N-Methylaspartate (NMDA)IBA
09/2009 - 02/2007
2Glutamic Acid (Glutamate)FDA Link
01/2023 - 10/2010
2Reactive Oxygen Species (Oxygen Radicals)IBA
01/2023 - 01/2016
2Cholic AcidIBA
11/2022 - 01/2018
2Complement System Proteins (Complement)IBA
01/2022 - 01/2020
2MicroRNAs (MicroRNA)IBA
10/2020 - 03/2016
2Vincristine (Oncovin)FDA LinkGeneric
01/2019 - 04/2013
2Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
01/2018 - 02/2014
2Histone Deacetylase InhibitorsIBA
01/2017 - 10/2006
2CytokinesIBA
01/2016 - 05/2004
2Genetic Markers (Genetic Marker)IBA
01/2016 - 09/2010
2ATP Binding Cassette Transporter 1IBA
01/2016 - 05/2005

Therapy/Procedure

19Therapeutics
01/2023 - 04/2005
3Immunotherapy
02/2024 - 04/2015
3Drug Therapy (Chemotherapy)
11/2017 - 12/2009